Wan, M., Héjjas, K., Rónai, Zs., Elek, Zs., Sasvári-Székely, M., Champagne, F.A., Miklósi, Á., Kubinyi, E.
Title of Experiment:
DRD4 and TH gene polymorphisms are associated with activity, impulsivity and inattention in Siberian Husky dogs (Category: Attention, Animal Species: dog)
Department of Psychology, Columbia University, Department of Medical Chemistry, Semmelweis University, Department of
Ethology, Eötvös University, MTA-ELTE Comparative Ethological Research Group
Both dopamine receptor D4 (DRD4) exon 3 and tyrosine hydroxylase (TH) intron 4 repeat polymorphisms have been linked to activity and impulsivity in German Shepherd dogs (GSDs). However, the results in GSDs may not be generalisable to other breeds, as allelic frequencies vary markedly among breeds. We selected the Siberian Husky for further study, because it is highly divergent from most dog breeds, including the GSD.